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br Conclusion This patient was hypercoaguable as evidenced
2021-04-19

Conclusion This patient was hypercoaguable as evidenced by a lower extremity DVT, pulmonary emboli, and a splenic infarct. Excluding acute CMV infectious mononucleosis, she had no disorders predisposing to splenic infarcts.4, 5 In this case, CMV infectious mononucleosis was accompanied by CMV lun
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cftr channel Introduction Primitive neuroectodermal tumors P
2021-04-19

Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met
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Mammalian cells contain significant amounts of a relatively
2021-04-19

Mammalian cells contain significant amounts of a relatively lesser known enzyme that shows marked specifity for ether lipids containing AA and other 20–22 carbon fatty acids. This enzyme is called CoA-independent transacylase (CoA-IT), and transfers polyunsaturated moieties of 20–22 carbons, typical
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The lack of effective strategies aiming to directly increase
2021-04-19

The lack of effective strategies, aiming to directly increase the neuronal survival, is reflected by the fact that the only available therapeutic interventions are indirect. They consist of acute therapeutic interventions involving chemical and/or surgical removal of the thrombotic clot (Taqi et al.
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Why then is leading strand DNA
2021-04-19

Why then is leading-strand DNA synthesis reduced relative to lagging-strand synthesis in rad53-1 mutant Aldicarb under replication stress? To gain insight into this question, we first determined whether the firing of late origins in rad53-1 mutant cells contributes to compromised leading-strand syn
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Altogether these data suggested that GlmU might be
2021-04-19

Altogether these data suggested that GlmU might be involved in the M. smegmatis biofilm mediated defence mechanisms. GlmU belongs to a metabolic pathway leading to UDP-GlcNAc from fructose-1-phosphate involved in the biosynthesis of peptidoglycan and lipopolysaccharide (Fig. 8). Recently, we demonst
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Several of the keloid like lesions
2021-04-19

Several of the keloid-like lesions seen in these individuals were pigmented. It is of potential relevance that genetic variants in DDR1 [MIM: 600408] have been associated with vitiligo, and DDR1 activation is involved when Abiraterone are attached to collagen-IV fibers. Because DDR1 and DDR2 are pa
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In contrast to DDR the role of oligomerization
2021-04-19

In VKGILS-NH2 synthesis to DDR1, the role of oligomerization and/or clustering of DDR2 in mediating its interactions with collagen is less understood. Current data show that in DDR2, like in DDR1, (i) dimerization [7] and higher-order oligomerization of its ECD [11], [22] enhance its binding to col
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Behaviors were compared between saline and amphetamine pre t
2021-04-17

Behaviors were compared between saline and amphetamine pre-treatment groups at 24h and 2 weeks following the last treatment, or between pre-treatment groups that received vehicle or ASV-30 infusions, using separate two-way ANOVAs. Significant effects were analyzed further using Student–Newman–Keuls
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SU 4312 The mechanisms in the central nervous system CNS
2021-04-17

The mechanisms in the central nervous system (CNS) controlling the sympathetic tone of the SU 4312 are associated to behavioral strategies, such as those involved in response to stress. In this regard, morphine withdrawal induces profound and severe stress reactions evidenced by enhancement of NA t
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br Experimental Procedures br Acknowledgments
2021-04-17

Experimental Procedures Acknowledgments Introduction Bisphenol A (BPA), 2,2-bis (4-hydroxyphenyl) propane, is widely used to manufacture consumer products including food and beverage containers (Vandenberg et al., 2007). It can be accumulated in human body via leaching from the polymers int
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Compression The L vertebral body was tested in compression
2021-04-17

Compression: The L4 vertebral body was tested in compression with loads applied along the craniocaudal axis using an Instron 8800 device at a rate of 3mm/min. Load displacement data were captured using Bluehill software. The ultimate load, yield load, stiffness, ultimate stress, yield stress and You
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Enhanced responses to varying concentrations of
2021-04-17

Enhanced responses to varying concentrations of bronchoconstrictors, such as MCh, and airway obstruction are characteristic of H-9 dihydrochloride and common to other clinical states, including chronic obstructive pulmonary disease, lung transplantation, and infection- or chemical agent-induced airw
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Our study found a significant association between the degree
2021-04-17

Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P naloxone hcl status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between EGFR mutat
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These cytokines except for TGF
2021-04-17

These cytokines, except for TGF-β can also increase CysLT1R mRNA expression. We further demonstrated that TGF-β and IL-13 were able to increase the proliferation of human BSMC in response to LTD4. BSMC proliferation was CysLT1R-dependent, given that Montelukast ablated this effect. Taken together, o
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