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It is common for plants that are deficient in P
2021-08-31
It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot teneligliptin ratio compared with plants in the INORG-P treatment. Additionally, greater allocation of C t
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br Other pathways involved in the preventive and
2021-08-31
Other pathways involved in the preventive and therapeutic potential of flavonoids in neurodegenerative diseases Rather than the induction of MAPK/ERK pathway, flavonoids actively modulate other critical intracellular neuronal survival and death protein kinases pathways, more importantly PI3K/Akt,
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The ultrafiltration approach has been used to
2021-08-31
The ultrafiltration approach has been used to measure equilibrium BIEs for a number of enzyme systems, including ciprofloxacin hexokinase (Lewis and Schramm, 2003a, Lewis and Schramm, 2003b), thymidine phosphorylase (Birck & Schramm, 2004), purine nucleoside phosphorylase (Murkin, Tyler, & Schramm,
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The N terminal amino acid sequence
2021-08-31
The N-terminal amino Sephin 1 sequence was made for STH2. This sequence showed high similarity (100%) with to trypsin-like found in the human airway classified as serine proteinase that also belongs to peptidase family SI and related also with chymotrypsin-like enzymes (Yasuoka et al., 1997). The s
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Here we discuss implications of several
2021-08-30
Here, we discuss implications of several major families of RING-type E3 ubiquitin ligases (MDM, Cullin, GRAIL, TRAF, TRIM) as targets in inflammation and immunity, and provide insights into potential small molecule interventions to mediate the cellular responses (summarized in Table 1). We briefly c
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The majority of APC C subunits form a
2021-08-30
The majority of APC/C subunits form a giant scaffold, which was originally named the arc lamp, based on its shape when viewing APC/C from one side (Figure 1 and Box 1) [24]. The scaffold consists of two modules: the TPR lobe resembles the curved post and lamp, and the platform resembles the engineer
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Although the ferromagnetic particles and T DNA ligase on the
2021-08-30
Although the ferromagnetic particles and T4 BMI-1 inhibitor on the particles were heated by the ac magnetic field, the average temperature of the reaction solution as a whole was kept suitably low for the annealing of DNA ends (16°C). Indeed, no appreciable increase in the temperature of the reacti
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br As mentioned above defects in the DNA
2021-08-30
As mentioned above, defects in the DNA ligase IIIα-interacting protein TDP1 have been identified as the cause of the hereditary neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy 1 (El-Khamisy et al., 2005). In addition, defects in two other DNA repair proteins, aprataxin and
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Our ex vivo analysis demonstrates that IL promotes CD expres
2021-08-30
Our ex vivo analysis demonstrates that IL-15 promotes CD122 expression in DGKζ-deficient CD8+ T cells. CD122, which forms a dimer with CD132 in response to IL-2 or IL-15, activates the JAK/STAT and PI3K/mTOR pathways. Whereas antigen-stimulated Z-YVAD-FMK promote IL-2 sensitivity through up-regulati
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A number of studies have been carried out to
2021-08-30
A number of studies have been carried out to understand lipid production pathways and to increase TAGs level in higher plants. Overexpression of key histone demethylase of the Kennedy pathway until now is by far the most successful strategy to increase TAG lipid content in Brassica napus, Arabidops
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For radiochemotherapy it is well known that
2021-08-30
For radiochemotherapy, it is well known that mitotic cell death and apoptosis present the major cell death modes. More recently, autophagy-dependent cell death has been described to occur upon radiochemotherapy (Daido et al., 2005, Song et al., 2017). This form of regulated cell death depends on com
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tmn IL is not expressed in
2021-08-30
IL-8 is not expressed in tissues constitutively because of its strong chemoattractant, proinflammatory, and angiogenic activities. Rather, it is an inducible factor, produced by a variety of cell types, including leukocytes, fibroblasts, endothelial and epithelial cells, in response to proinflammato
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br Conflict of interest br Acknowledgments Part of
2021-08-30
Conflict of interest Acknowledgments Part of this work was supported by Institut Francais en Egypte, and the Academy of Scientific Research and Technology in Egypt under the frame of “Imhotep Project N°: 31681XL” and “STDF/IFE project N° 30630″ Introduction NSAIDs play an important role in
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Survival analysis has been widely used in medical science
2021-08-30
Survival analysis has been widely used in medical science, economics, finance, and social science, among others. In many studies, survival data have primary outcomes or responses that are subject to censoring. The Cox model [7], [8] is the most commonly used regression model for survival data, and t
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Collectively these data suggest the
2021-08-30
Collectively, these data suggest the potential clinical utility of COMT inhibitors for the treatment of addiction disorders. Similar to current pharmacotherapies such as naltrexone, tolcapone's effects were not ethanol specific, therefore tolcapone may be effective in reducing other drug reinforced
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