• The approach of enzymatically converting an analyte

  2024-04-07

  

  The approach of enzymatically converting an analyte and detecting it by the resulting small pH changes near the reduced graphene oxide (rGO) surface has successfully been pursued in case of urea (Piccinini et al., 2017). Furthermore, this work reported that electrostatic layer-by-layer (LbL) assembl

• br Funding This work was

  2024-04-07

  

  Funding This work was supported by the National Natural Science Foundation of China (grant No. 81573664). Thanks to Jing-xian Yang from the Pharmacology Laboratory of Liaoning University of Traditional Chinese Medicine for support with technology and experimental equipment. Disclosure Confl

• In spite of this unexpectedly after three

  2024-04-07

  

  In spite of this, unexpectedly, after three-week cherry puree consumption no AC increase was observed, irrespective of the method used (Table 2). A statistically significant decrease of AC was even measured by LOX-FL and ORAC methods (−3.5% and −9%, respectively). Nevertheless, a much more evident d

• Infections inflammation and corneal transplant can all cause

  2024-04-07

  

  Infections, inflammation, and corneal transplant can all cause corneal neovascularization via upregulation of inflammatory cytokines, which attract myeloid 76 2 receptor into the cornea. These myeloid cells establish a cycle of cytokine secretion and further myeloid cell recruitment in the cornea.

• Platelet derived growth factor PDGF

  2024-04-07

  

  Platelet-derived growth factor (PDGF) and ciliary neurotrophic factor (CNTF) are expressed by glial MMP-2 Inhibitor II and are important to neuron survival and the maintenance of oligodendrocytes. These neurotrophic factors contribute to the remyelination process by increasing the proliferation of

• LOXs and CYPs are a series of iron containing

  2024-04-07

  

  LOXs and CYPs are a series of iron-containing enzymes that metabolize arachidonic Sulfo-NHS-SS-Biotin synthesis to form biologically active products, such as epoxyeicosatrienoic acids (EETs) hydroperoxyeicosatetraenoic acids (HETEs), prostaglandins, leukotrienes and thromboxanes [6]. Among these med

• Ala a branched chain amino acid has been reported to

  2024-04-07

  

  Ala, a branched chain amino acid, has been reported to play a functional role in intracellular pH regulation, and it typically accumulates in response to various stresses (Limami et al., 2008, Rocha et al., 2010). Our data demonstrated that increasing Cd concentrations at lower Cd doses resulted in

• Silk which is a mixture of mainly

  2024-04-07

  

  Silk, which is a mixture of mainly SF and sericin, has an extensive history in clinical application as a suture material. Unwanted immune reactions to silk sutures observed early on in their application were assigned to the presence of sericin. However, in vitro and in vivo evaluations of pure SF fi

• br Conclusions The following are the supplementary data rela

  2024-04-07

  

  Conclusions The following are the supplementary data related to this article. Author contributions Conflict of interest Funding sources This work was supported by the Canadian Institutes of Health Research [grant: MOP-79470]. Introduction Sperm cells undergo a number of physical and

• br Acknowledgments This work was supported by a grant

  2024-04-03

  

  Acknowledgments This work was supported by a grant of the Romanian National Authority for Scientific Research, CNCS – UEFISCDI, project no. PN-II-ID-PCE-2011-3-0571, awarded to F.A.M. D.V.N. was co-financed from the European Social Fund through Sectorial Operational Program Human Resources Develo

• The benzimidazole group seems to be a key feature

  2024-04-03

  

  The benzimidazole group seems to be a key feature for the excellent anti-tumor activity of galeterone (159), which motivated the synthesis of new steroidal inhibitors containing N-heterocyclic groups structurally related to benzimidazole. Thus, several 1H- and 2H-indazole derivatives of dehydroepian

• Apoptosis signal regulating kinase ASK

  2024-04-03

  

  Apoptosis signal-regulating kinase 1 (ASK1, also referred to as MAP3K5)(Ichijo et al., 1997) participates in many different stress responses, including apoptosis (Chang et al., 1998, Chen et al., 1999, Ichijo et al., 1997, Kanamoto et al., 2000, Noguchi et al., 2008, Saitoh et al., 1998, Tobiume et

• Compound was synthesized by reacting amino methoxybenzoate

  2024-04-03

  

  Compound 31 was synthesized by reacting 5-amino-2-methoxybenzoate (28) with ethanesulfonyl chloride in the presence of pyridine in DCM to give sulfonamide 29. Hydrolysis of 29 by aqueous sodium hydroxide afforded the Cyprodime hydrochloride australia 30 which was converted to the acid chloride by h

• alcohol dehydrogenase inhibitor Chlorogenic acid an abundant

  2024-04-03

  

  Chlorogenic alcohol dehydrogenase inhibitor (7), an abundant polyphenol found in coffee and the human diet, has various biological activities including antioxidant and anticancer effects [54]. Jiang et al. reported that compound 7 had a selective cytotoxic activity on human oral tumor cells (HSG, H

• br Materials and methods br Results br Discussion

  2024-04-03

  

  Materials and methods Results Discussion In this study, we administrated BDE-153 to newborn rat pups at PND 10 and cultured primary neurons, measured neuronal apoptosis and LDH activity in vivo and in vitro, then explored the possible predominant pathway underlying the neuronal apoptosis by

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